Julho/Agosto/Setembro 2015

Caros amigos, enviamos mais uma edição de nosso informativo da imagem do

departamento de imagem da SBPT. Este informativo visa trazer mensalmente os

artigos mais interessantes da área e ira revisar os seguintes jornais: Radiology,

American Journal of Roentgenology, Chest, Thorax, Lung, AJRCCM, Respiratory

Medicine, European radiology, European Journal of Radiology, Academic radiology, e

Journal of thoracic Imaging. Além disso divulgaremos todo trabalho enviado por algum

membro do departamento que tenha interesse!

Um forte abraço a todos.

Departamento de Imagem da SBPT

Sugestões: brunohochhegger@gmail.com

Three-way Comparison of Whole-Body MR, Coregistered Whole-Body FDG PET/MR, and Integrated Whole-Body FDG PET/CT Imaging: TNM and Stage Assessment Capability for Non–Small Cell Lung Cancer Patients Artigo demonstra que a ressonância de corpo inteiro é um método excelente para estadiar o câncer de pulmão e superior ao PET/CT e similar ao PET/RM. Purpose To prospectively compare the capabilities for TNM classification and assessment of clinical stage and operability among whole-body magnetic resonance (MR) imaging, coregistered positron emission tomographic (PET)/MR imaging with and without MR signal intensity (SI) assessment, and integrated fluorine 18 fluorodeoxyglucose (FDG) PET/computed tomography (CT) in non–small cell lung cancer (NSCLC) patients. Materials and Methods The institutional review board approved this study, and written informed consent was obtained from each patient. One hundred forty consecutive NSCLC patients (75 men, 65 women; mean age, 72 years) prospectively underwent whole-body MR imaging, FDG PET/CT, conventional radiologic examinations, and surgical, pathologic, and/or follow-up examinations. All factors and clinical stage and operability were then visually assessed. All PET/MR examinations were assessed with and without SI assessment. One examination used anatomic, metabolic, and relaxation-time information, and the other used only anatomic and metabolic information. κ statistics were used for assessment of all factors and clinical stages with final diagnoses. McNemar test was used to compare the capability of all methods to assess operability. Results Agreements of assessment of every factor (κ = 0.63–0.97) and clinical stage (κ = 0.65–0.90) were substantial or almost perfect. Regarding capability to assess operability, accuracy of whole-body MR imaging and PET/MR imaging with SI assessment (97.1% [136 of 140]) was significantly higher than that of MR/PET without SI assessment and integrated FDG PET/CT (85.0% [119 of 140]; P < .001). Conclusion Accuracies of whole-body MR imaging and PET/MR imaging with SI assessment are superior to PET/MR without SI assessment and PET/CT for identification of TNM factor, clinical stage, and operability evaluation of NSCLC patients.

Artigo que realiza uma revisão prática e completa das massas mediastinais

Imaging Evaluation of Mediastinal Masses in Children and Adults: Practical Diagnostic Approach Based on A New Classification System Thacker, Paul G. MD*; Mahani, Maryam G. MD†; Heider, Amer MD‡; Lee, Edward Y. MD, MPH§ Free Access Continued Medical Education

Abstract

A compartmental approach to the diagnosis of the mediastinal masses in children and adults has been widely used to facilitate the diagnosis and planning of diagnostic interventions and surgical treatment for many years. Recently, a new computed tomography–based mediastinal division scheme, approved by the International Thymic Malignancy Interest Group, has received considerable attention as a potential new standard. In this review article, this new computed tomography–based mediastinal division scheme is described and illustrated. In addition, currently used imaging modalities and techniques, practical imaging algorithm of evaluating mediastinal masses, and characteristic imaging findings of various mediastinal masses that occur in children and adults are discussed. Such up-to-date knowledge has the potential to facilitate better understanding of mediastinal masses in both pediatric and adult populations.

Thorax 2015;70:725-731 doi:10.1136/thoraxjnl-2014-206160

Incidental findings on chest CT imaging are associated with increased COPD exacerbations and mortality . Pushpa M Jairam1,2, Yolanda van der Graaf1, Jan-Willem J Lammers3,

Willem P Th M Mali2, Pim A de Jong2 on behalf of the PROVIDI Study group

+ Artigo demonstra que enfisema e broncopatia, mesmo que identificados incidentalmente, são preditores de pior prognóstico na DPOC

Abstract Background This study aimed to evaluate whether incidental CT findings of emphysema, airway thickening and bronchiectasis, as seen on CT scans performed for other non-pulmonary clinical indications, are associated with future acute exacerbations of COPD resulting in hospitalisation or death.

Methods This multicentre prospective case–cohort study comprised 6406 subjects who underwent routine diagnostic chest CT for non-pulmonary indications. Using a case–cohort approach, we visually graded CT scans from cases and a random sample of ∼10% of the baseline cohort (n=704) for emphysema severity (range 0–20), airway thickening (range 0–5) and bronchiectasis (range 0–5). We used weighted Cox proportional hazards analysis to assess the independent association between CT findings and hospitalisation or death due to COPD exacerbation.

Results During a median follow-up of 4.4 years (maximum 5.2 years), 338 COPD events were identified. The risk of experiencing a future acute exacerbation of COPD resulting in hospitalisation or death was significantly increased in subjects with severe emphysema (score ≥7) and severe airway thickening (score ≥3). The respective HRs were 4.6 (95% CI 3.0 to 7.1) and 5.9 (95% CI 3.4 to 10.5). Severe bronchiectasis (score ≥3) was not significantly associated with increased risk of adverse events (HR 1.5; 95% CI 0.9 to 2.5).

Conclusions Morphological correlates of COPD such as emphysema and airway thickening detected on CT scans obtained for other non-pulmonary indications are strong independent predictors of subsequent development of acute exacerbations of COPD resulting in hospitalisation or death.

Artigo demonstra o posicionamento da sociedade de radiologia e pneumologia da Europa a respeito do rastreamento do câncer de Pulmão, que recomenda o mesmo com observações importantes.

ESR/ERS white paper on lung cancer screening Lung cancer is the most frequently fatal cancer, with poor survival once the disease is advanced. Annual low dose computed tomography has shown a survival benefit in screening individuals at high risk for lung cancer. Based on the available evidence, the European Society of Radiology and the European Respiratory Society recommend lung cancer screening in comprehensive, quality-assured, longitudinal programmes within a clinical trial or in routine clinical practice at certified multidisciplinary medical centres. Minimum requirements include: standardised operating procedures for low dose image acquisition, computer-assisted nodule evaluation, and positive screening results and their management; inclusion/exclusion criteria; expectation management; and smoking cessation programmes. Further refinements are recommended to increase quality, outcome and cost-effectiveness of lung cancer screening: inclusion of risk models, reduction of effective radiation dose, computer-assisted volumetric measurements and assessment of comorbidities (chronic obstructive pulmonary disease and vascular calcification). All these requirements should be adjusted to the regional infrastructure and healthcare system, in order to exactly define eligibility using a risk model, nodule management and quality assurance plan. The establishment of a central registry, including biobank and image bank, and preferably on a European level, is strongly encouraged.

Chronic Obstructive Pulmonary Disease: Pulmonary Function and CT Lung Attenuation Do Not Show Linear Correlation Artigo demonstra que os achados radiológicos de DPOC não tem correlação linear com os achados de função pulmonar. Purpose To determine whether the relationship between pulmonary function and computed tomographic (CT) lung attenuation in chronic obstructive pulmonary disease (COPD), which is traditionally described with single univariate and multivariate statistical models, could be more accurately described with a multiple model estimation approach. Materials and Methods The study was approved by the local ethics committee. All participants provided written informed consent. The prediction of the percentage area with CT attenuation values less than −950 HU at inspiration (%LAA−950insp) and less than −910 HU at expiration (%LAA−910exp) obtained with single univariate and multivariate models was compared with that obtained with a multiple model estimation approach in 132 patients with COPD. Results At univariate analysis, %LAA−950insp and %LAA−910exp values higher than the mean value of this cohort (19.1% and 22.0%) showed better correlation with percentage of predicted diffusing capacity of lung for carbon monoxide (Dlco%) than with airflow obstruction (forced expiratory volume in 1 second [FEV1]/vital capacity [VC]). Conversely, %LAA−950insp and %LAA−910exp values lower than the mean value were correlated with FEV1/VC but not with Dlco%. Multiple model estimation performed with two multivariate regressions, each selecting the most appropriate functional variables (FEV1/VC for mild parenchymal destruction, Dlco% and functional residual capacity for severe parenchymal destruction), predicted better than single multivariate regression both %LAA−950insp (R2 = 0.75 vs 0.46) and %LAA−910exp (R2 = 0.83 vs 0.63). Conclusion The relationship between pulmonary function data and CT densitometric changes in COPD varies with the level of lung attenuation impairment. The nonlinear profile of this relationship is accurately predicted with a multiple model estimation approach.

American Journal of Roentgenology Overdiagnosis of Pulmonary Embolism by Pulmonary CT Angiography Artigo demonstra que frequentemente existe aumento errôneo dos diagnósticos de embolia na TC. OBJECTIVE. The purpose of this study is to evaluate the rate of overdiagnosis of pulmonary embolism (PE) by pulmonary CT angiography (CTA) in a tertiary-care university hospital. MATERIALS AND METHODS. This study is a retrospective review of all pulmonary CTA examinations performed in a tertiary-care university hospital over a 12-month period. Studies originally reported as positive for PE were retrospectively reinterpreted by three subspecialty chest radiologists with more than 10 years’ experience. A pulmonary CTA was considered negative for PE when all three chest radiologists were in agreement that the pulmonary CTA study was negative for PE. The location and potential causes for PE overdiagnosis were recorded. RESULTS. A total of 937 pulmonary CTA studies were performed over the study period. PE was diagnosed in the initial report in 174 of these cases (18.6%). There was discordance between the chest radiologists and the original radiologist in 45 of 174 (25.9%) cases. Discordance occurred more often where the original reported PE was solitary (46.2% of reported solitary PEs were considered negative on retrospective review) and located in a segmental or subsegmental pulmonary artery (26.8% of segmental and 59.4% of subsegmental PE diagnoses were considered negative on retrospective review). The most common cause of diagnostic difficulty was breathing motion artifact, followed by beam-hardening artifact. CONCLUSION. In routine clinical practice, PEs diagnosed by pulmonary CTA are frequently overdiagnosed, when compared with the consensus opinion of a panel of expert chest radiologists. Improvements in the quality of pulmonary CTA examination and increased familiarity with potential diagnostic pitfalls in pulmonary CTA are recommended to minimize misdiagnosis of PE.

American Journal of Roentgenology Ultra-Low-Dose CT of the Thorax Using Iterative Reconstruction: Evaluation of Image Quality and Radiation Dose Reduction Artigo demonstra a viabilidade de tomografias com doses semelhantes a de uma radiografia de tórax OBJECTIVE. The purpose of this study is to assess the image quality and radiation dose reduction of ultra-low-dose CT using sinogram-affirmed iterative reconstruction (SAFIRE). SUBJECTS AND METHODS. This prospective study enrolled 25 patients who underwent three consecutive unenhanced CT scans including low-dose CT (120 kVp and 30 mAs) and two ultra-low-dose CT protocols (protocol A, 100 kVp and 20 mAs; protocol B, 80 kVp and 30 mAs) with image reconstruction using SAFIRE. The image quality and radiation dose reduction were assessed. RESULTS. The mean (± SD) effective radiation dose was 1.06 ± 0.11, 0.44 ± 0.05, and 0.31 ± 0.03 mSv for low-dose CT, ultra-low-dose CT protocol A, and ultra-low-dose CT protocol B, respectively. Overall image quality was determined as diagnostic in 100% of low-dose CT scans, 96% of ultra-low-dose CT protocol A scans, and 88% of ultra-low-dose CT protocol B scans. All patients with nondiagnostic quality images had a body mass index (weight in kilograms divided by the square of height in meters) greater than 25. There was no statistically significant difference in detection frequencies of 14 lesion types among the three CT protocols, but pulmonary emphysema was detected in fewer patients (3/25) in ultra-low-dose CT protocol B scans compared with ultra-low-dose CT protocol A scans (5/25) or low-dose CT scans (6/25). We measured the longest dimensions of 33 small solid nodules (3.8–12.4 mm in long diameter) and found no statistically significant difference in the values afforded by the three CT protocols (p = 0.135). CONCLUSION. Iterative reconstruction allows ultra-low-dose CT and affords acceptable image quality, allowing size measurements of solid pulmonary nodules to be made.

ARTIGOS PUBLICADOS PELOS MEMBROS DO DEPARTAMENTO: 1. Computed tomographic pulmonary changes in patients with chronic rhinosinusitis. Hochhegger B, Alves GR, Irion KL, Watte G, Scheeren B, Rottenfuser R, Marchiori E. Br J Radiol. 2015 Aug 6:20150273. [Epub ahead of print] PMID: 26246280 2. Management of Ossifying Fibroma in a Suspicious Case of Hyperparathyroid-Jaw Tumor Syndrome. Marchiori ÉC, Isom BA, Indresano AT. Craniomaxillofac Trauma Reconstr. 2015 Sep;8(3):228-33. doi: 10.1055/s-0034-1395381. Epub 2014 Dec 2. PMID: 26269732 3. Lung and Chest-Wall Metastasis of Liposarcoma. Barreto MM, Fortes HR, Valiante PM, Zanetti G, Marchiori E. Lung. 2015 Aug 8. [Epub ahead of print] No abstract available. PMID: 26253776 4. Computed tomography in the diagnosis of bronchiectasis. Amaral RH, Schuler Nin C, de Souza VV, Marchiori E, Hochhegger B. Eur Respir J. 2015 Aug;46(2):576-7. doi: 10.1183/09031936.00031415. No abstract available. PMID: 26232484 5. Placental Transmogrification of the Lung. Hochhegger B, Camargo S, Camargo J, Barreto MM, Zanetti G, Marchiori E. Lung. 2015 Jul 26. [Epub ahead of print] No abstract available. PMID: 26210476 6. Superior Vena Cava Lipoma in an Asymptomatic Man. Concatto NH, Camargo S, Camargo J, Hochhegger B, Irion K, Marchiori E. Lung. 2015 Jul 25. [Epub ahead of print] PMID: 26209037 7. The importance of the reviewers. Marchiori E. Radiol Bras. 2015 May-Jun;48(3):V. doi: 10.1590/0100-3984.2015.48.3e1. No abstract available. PMID: 26185353 Free PMC Article 8. Reversed halo sign in acute schistosomiasis. Souza AS Jr, Souza AS, Soares-Souza L, Zanetti G, Marchiori E.

J Bras Pneumol. 2015 May-Jun;41(3):286-8. doi: 10.1590/S1806-37132015000004444. English, Portuguese. No abstract available. PMID: 26176529 Free Article 9. PET/CT imaging in lung cancer: indications and findings. Hochhegger B, Alves GR, Irion KL, Fritscher CC, Fritscher LG, Concatto NH, Marchiori E. J Bras Pneumol. 2015 May-Jun;41(3):264-74. doi: 10.1590/S1806-37132015000004479. English, Portuguese. PMID: 26176525 Free Article 10. Small interstitial nodules. Marchiori E, Zanetti G, Hochhegger B. J Bras Pneumol. 2015 May-Jun;41(3):250. doi: 10.1590/S1806-37132015000000059. English, Portuguese. No abstract available. PMID: 26176523 Free Article 11. Organizing pneumonia: chest HRCT findings. Faria IM, Zanetti G, Barreto MM, Rodrigues RS, Araujo-Neto CA, Silva JL, Escuissato DL, Souza AS Jr, Irion KL, Mançano AD, Nobre LF, Hochhegger B, Marchiori E. J Bras Pneumol. 2015 May-Jun;41(3):231-7. doi: 10.1590/S1806-37132015000004544. English, Portuguese. PMID: 26176521 Free Article 12. The role of imaging in suspected pulmonary artery tumors. Marchiori E, Zanetti G, Hochhegger B. Arch Bronconeumol. 2015 Jul 4. pii: S0300-2896(15)00197-0. doi: 10.1016/j.arbres.2015.05.013. [Epub ahead of print] English, Spanish. No abstract available. PMID: 26153561 Free Article 13. Pulmonary and Breast Tuberculosis: An Unusual Association. Bazi-Fontes F, Zanetti G, Marchiori E. Arch Bronconeumol. 2015 Jul 4. pii: S0300-2896(15)00198-2. doi: 10.1016/j.arbres.2015.05.014. [Epub ahead of print] English, Spanish. No abstract available. PMID: 26153560 Free Article 14. The role of imaging methods in the diagnosis of pulmonary lipoma. Menna-Barreto M, Zanetti G, Marchiori E. Arch Bronconeumol. 2015 Jul 4. pii: S0300-2896(15)00201-X. doi: 10.1016/j.arbres.2015.04.014. [Epub ahead of print] English, Spanish. No abstract available. PMID: 26153558 Free Article

15. A Giant Cell Tumor Arising from the Anterior Costal Arc in a Young Man. Cavaguti RF, Barreto MM, Valiante PM, Zanetti G, Marchiori E. Lung. 2015 Jun 24. [Epub ahead of print] No abstract available. PMID: 26104491 16. Tuberous Sclerosis Complex: State-of-the-Art Review with a Focus on Pulmonary Involvement. von Ranke FM, Zanetti G, E Silva JL, Neto CA, Godoy MC, Souza CA, Mançano AD, Souza AS Jr, Escuissato DL, Hochhegger B, Marchiori E. Lung. 2015 Jun 24. [Epub ahead of print] PMID: 26104489 17. Differential diagnosis of diffuse alveolar haemorrhage in immunocompromised patients. Escuissato DL, Warszawiak D, Marchiori E. Curr Opin Infect Dis. 2015 Aug;28(4):337-42. doi: 10.1097/QCO.0000000000000181. PMID: 26098496 18. Focal pleural tumorlike conditions: Nodules and masses beyond mesotheliomas and metastasis. Fernandes de Paula MC, Escuissato DL, Belém LC, Zanetti G, Souza AS Jr, Hochhegger B, Nobre LF, Marchiori E. Respir Med. 2015 Jun 12. pii: S0954-6111(15)30006-8. doi: 10.1016/j.rmed.2015.06.004. [Epub ahead of print] Review. PMID: 26094051 19. Calcified multinodular lung lesions: a broad differential diagnosis. Zanetti G, Hochhegger B, Marchiori E. Clin Respir J. 2015 Jun 16. doi: 10.1111/crj.12338. [Epub ahead of print] No abstract available. PMID: 26076975 20. Acute pulmonary embolism following endoscopic glue injection for sclerotherapy. de Freitas Ribeiro BN, Sobral de Magalhães Oliveira AL, Marchiori E. Arch Bronconeumol. 2015 Jun 8. pii: S0300-2896(15)00133-7. doi: 10.1016/j.arbres.2015.03.017. [Epub ahead of print] English, Spanish. No abstract available. PMID: 26067098 Free Article 21. Pneumothorax related to lung cysts and renal masses. Pereira E Silva JL, Araujo Neto CA, Marchiori E. Arch Bronconeumol. 2015 Jun 3. pii: S0300-2896(15)00129-5. doi: 10.1016/j.arbres.2015.02.018. [Epub ahead of print] English, Spanish. No abstract available.

PMID: 26049763 Free Article 22. Mechanical and photoelastic analysis of conventional screws and cannulated screws for sagittal split osteotomy fixation: a comparative study. de Lima CJ, Falci SG, Rodrigues DC, Marchiori ÉC, Moreira RW. Oral Maxillofac Surg. 2015 Jun 6. [Epub ahead of print] PMID: 26044646 23. A curious case of pill aspiration. Hochhegger B, Irion KL, Zanetti G, Marchiori E. Chest. 2015 Jun;147(6):e234-5. doi: 10.1378/chest.15-0184. No abstract available. PMID: 26033144 24. Enhancing survival with early surgical resection of endobronchial metastasis in a follow-up of ovarian carcinoma. Franco RM, Guimaraes MD, Moreira BL, Bitencourt AG, Hochhegger B, Marchiori E. Radiol Bras. 2015 Mar-Apr;48(2):130. doi: 10.1590/0100-3984.2013.0020. No abstract available. PMID: 25987757 Free PMC Article 25. Catamenial pneumothorax. Barbosa BC, Marchiori E, Zanetti GM, Barillo JL. Radiol Bras. 2015 Mar-Apr;48(2):128-9. doi: 10.1590/0100-3984.2014.0067. No abstract available. PMID: 25987756 Free PMC Article 26. Intestinal and appendiceal paracoccidioidomycosis. Gava P, de Melo AS, Marchiori E, Costa MH, Pereira E, Rangel RD. Radiol Bras. 2015 Mar-Apr;48(2):126-7. doi: 10.1590/0100-3984.2014.0035. No abstract available. PMID: 25987754 Free PMC Article 27. Whole-body magnetic resonance imaging in children: state of the art. Teixeira SR, Elias Junior J, Nogueira-Barbosa MH, Guimarães MD, Marchiori E, Santos MK. Radiol Bras. 2015 Mar-Apr;48(2):111-20. doi: 10.1590/0100-3984.2014.0005. Review. PMID: 25987752 Free PMC Article 28. Iodinated contrast media and its influence in emphysema CT measurements. Hochhegger B, Marchiori E, Irion KL, Zanetti G. Clin Imaging. 2015 Mar 30. pii: S0899-7071(11)00133-1. doi: 10.1016/j.clinimag.2011.06.008. [Epub ahead of print] No abstract available. PMID: 25835586 29. Changes in radiologia brasileira for 2015. Marchiori E.

Radiol Bras. 2015 Jan-Feb;48(1):v. doi: 10.1590/0100-3984.2015.48.1e1. No abstract available. PMID: 25798016 Free PMC Article 30. Giant pilomatrixoma: conventional and diffusion-weighted magnetic resonance imaging findings. Ribeiro BN, Marchiori E. Radiol Bras. 2015 Jan-Feb;48(1):63-4. doi: 10.1590/0100-3984.2014.0071. No abstract available. PMID: 25798014 Free PMC Article 31. Peripheral primitive neuroectodermal tumor of chest wall in young adult. Silva GM Junior, Zanetti GM, Barillo JL, Marchiori E. Radiol Bras. 2015 Jan-Feb;48(1):60-61. No abstract available. PMID: 25798010 Free PMC Article 32. Magnetic resonance imaging of the chest in the evaluation of cancer patients: state of the art. Guimaraes MD, Hochhegger B, Santos MK, Santana PR, Sousa AS Júnior, Souza LS, Marchiori E. Radiol Bras. 2015 Jan-Feb;48(1):33-42. PMID: 25798006 Free PMC Article 33. Hibernoma: an uncommon cause of a pleural mass. Marchiori E, Zanetti G, Hochhegger B. J Bras Pneumol. 2015 Jan-Feb;41(1):103-4. doi: 10.1590/S1806-37132015000100015. No abstract available. PMID: 25750682 Free PMC Article 34. Intrapulmonary mature teratoma mimicking a fungus ball. Barreto MM, Valiante PM, Zanetti G, Boasquevisque CH, Marchiori E. Lung. 2015 Jun;193(3):443-5. doi: 10.1007/s00408-015-9709-7. Epub 2015 Mar 7. No abstract available. PMID: 25749667 35. Which is your diagnosis? Gadelha Terceiro M, Faria IM, de Paula RA, Marchiori E. Radiol Bras. 2014 Nov-Dec;47(6):XI-XIII. doi: 10.1590/0100-3984.2014.47.6qd. No abstract available. PMID: 25741128 Free PMC Article 36. Which is your diagnosis? Fernandes MC, Zanetti G, Hochhegger B, Marchiori E. Radiol Bras. 2014 May-Jun;47(3):XI-XIII. doi: 10.590/0100-3984.2014.47.3qd. No abstract available. PMID: 25741084 Free PMC Article

37. Functional magnetic resonance imaging in oncology: state of the art. Guimaraes MD, Schuch A, Hochhegger B, Gross JL, Chojniak R, Marchiori E. Radiol Bras. 2014 Mar-Apr;47(2):101-11. doi: 10.1590/S0100-39842014000200013. Review. PMID: 25741058 Free PMC Article 38. Evaluation of the adequacy of reference charts for the accurate identification of fetuses with bone length below the 5th percentile. de Carvalho AA, Carvalho JA, Figueiredo I, Velarde LG, Marchiori E. J Perinat Med. 2015 Jan 17. pii: /j/jpme.ahead-of-print/jpm-2014-0239/jpm-2014-0239.xml. doi: 10.1515/jpm-2014-0239. [Epub ahead of print] PMID: 25720035 39. Teratoma: another cause of the air crescent sign. Marchiori E, Zanetti G, Barreto MM. QJM. 2015 May;108(5):431. doi: 10.1093/qjmed/hcv034. Epub 2015 Feb 5. No abstract available. PMID: 25660602 40. Local quality functions for graph clustering with non-negative matrix factorization. van Laarhoven T, Marchiori E. Phys Rev E Stat Nonlin Soft Matter Phys. 2014 Dec;90(6):062813. Epub 2014 Dec 29. PMID: 25615154 41. Imaging acute complications in cancer patients: what should be evaluated in the emergency setting? Guimaraes MD, Bitencourt AG, Marchiori E, Chojniak R, Gross JL, Kundra V. Cancer Imaging. 2014 Apr 29;14:18. doi: 10.1186/1470-7330-14-18. PMID: 25609051 Free PMC Article 42. Mechanical and photoelastic analysis of four different fixation methods for mandibular body fractures. Rodrigues DC, Falci SG, Lauria A, Marchiori ÉC, Moreira RW. J Craniomaxillofac Surg. 2015 Apr;43(3):306-11. doi: 10.1016/j.jcms.2014.11.021. Epub 2014 Nov 28. Select item 25563772 43. An uncommon complication of staphylococcal pneumonia: pneumopericardium with cardiac tamponade. Marchiori E, Canella C, Hochhegger B, Zanetti G. Thorax. 2015 Apr;70(4):395. doi: 10.1136/thoraxjnl-2014-206642. Epub 2015 Jan 6. No abstract available. PMID: 25563772 44. Mediastinal lymph nodes and pulmonary nodules in children: MDCT findings in a cohort of healthy subjects.

Alves GR, Marchiori E, Irion KL, Guimarães MD, da Cunha CF, de Souza VV, Hochhegger B. AJR Am J Roentgenol. 2015 Jan;204(1):35-7. doi: 10.2214/AJR.14.12773. PMID: 25539235 45. Birt-Hogg-Dubé syndrome. State-of-the-art review with emphasis on pulmonary involvement. Dal Sasso AA, Belém LC, Zanetti G, Souza CA, Escuissato DL, Irion KL, Guimarães MD, Marchiori E. Respir Med. 2015 Mar;109(3):289-96. doi: 10.1016/j.rmed.2014.11.008. Epub 2014 Dec 9. Review. PMID: 25519092 46. Improving CT-guided transthoracic biopsy of mediastinal lesions by diffusion-weighted magnetic resonance imaging. Guimarães MD, Hochhegger B, Benveniste MF, Odisio BC, Gross JL, Zurstrassen CE, Tyng CC, Bitencourt AG, Marchiori E. Clinics (Sao Paulo). 2014 Nov;69(11):787-91. doi: 10.6061/clinics/2014(11)13. PMID: 25518038 Free PMC Article 47. Ankylosing spondylitis with bulbar syndrome and atlantoaxial synovitis. Aniceto Moreira L, Amorim RB, Gómez VE, Canella C, Bacchiega AB, Marchiori E. J Rheumatol. 2014 Dec;41(12):2484-5. doi: 10.3899/jrheum.140165. No abstract available. PMID: 25452181 48. Measuring relief of dysphagia in locally advanced esophageal carcinoma patients submitted to high-dose-rate brachytherapy. Grazziotin Reisner R, Reisner ML, Ferreira MA, Rosa AA, Veras IM, Carneiro TM, Wolff B, Viégas CM, Mendonça de Araújo CM, Marchiori E. Brachytherapy. 2015 Jan-Feb;14(1):84-90. doi: 10.1016/j.brachy.2014.09.007. Epub 2014 Oct 30. PMID: 25447340 49. Sandblasting in the naval industry: another life-threatening activity related to silicosis. Marchiori E, Barreto MM, Zanetti G. Arch Bronconeumol. 2015 Feb;51(2):101-2. doi: 10.1016/j.arbres.2014.08.009. Epub 2014 Oct 22. English, Spanish. No abstract available. PMID: 25446865 Free Article 50. Thoracic endometriosis: the role of imaging. Marchiori E, Hochhegger B, Zanetti G. Arch Bronconeumol. 2015 Apr;51(4):202. doi: 10.1016/j.arbres.2014.04.013. Epub 2014 Nov 3. English, Spanish. No abstract available. PMID: 25443588 Free Article